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Efavirenz

Efavirenz Coupons & Discount Card – Guaranteed Prices from $173.13

generic Sustiva

Efavirenz, also known as Sustiva, is a medication used in combination with other antiretroviral drugs to manage HIV infections in individuals aged three months and older. It is classified as a non-nucleoside reverse transcriptase inhibitor (NNRTI) and works by blocking an enzyme called reverse transcriptase. This action prevents HIV from replicating and spreading, thereby reducing the amount of the virus in the body. Consequently, this helps strengthen the immune system and lowers the risk of developing complications such as infections and cancer, ultimately enhancing quality of life. Efavirenz is available in oral tablets and capsules. For those who have difficulty swallowing, the capsules can be opened and mixed with liquid. While it is not a cure for HIV, continuing treatment as prescribed is crucial for effectiveness. It is also important to use barrier methods like condoms during sexual activity and avoid sharing personal items that may come into contact with blood or body fluids to reduce the risk of transmitting the virus to others. Common side effects of Efavirenz include rash, diarrhea, and nausea. It is available as both a brand-name and generic medication. Always consult your healthcare provider for personalized medical advice and follow their instructions closely.
Our coupons are free to use. Before paying, show the pharmacist your Efavirenz savings card to get your free discount. Use our filters below to edit the prescription box to match your needs. The Efavirenz prices will update based on your prescription needs. Above our Efavirenz coupons, you can change your location to see pharmacy prices and costs in other areas. We're here to help you buy Efavirenz at the lowest price with our prescription discount card.
Efavirenz WarningsEfavirenz Side EffectsEfavirenz InteractionsFAQs

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200MG, Efavirenz (30 Capsules)

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$173.13

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Efavirenz dosage forms

The average cost for 30 Capsules of Efavirenz (generic Sustiva) at 50MG is $53.76 with a free coupon. This is 94% off the average retail price of $899.76
DosageQuantityPrice fromPer unit
50MG30 Capsules$53.76$1.79
200MG30 Capsules$175.5$5.85

Efavirenz Warnings

The following safety information is crucial for anyone considering or currently using efavirenz (Sustiva). Please read carefully and discuss any concerns with your healthcare provider.

  • Heart Rhythm Concerns: Efavirenz can lead to serious heart rhythm issues, known as QT prolongation, which may be life-threatening. Individuals with a history of heart problems, slow heart rate, or those on medications like amiodarone that also affect heart rhythm, are at heightened risk. If you experience chest discomfort, breathing difficulties, or faintness, seek emergency assistance immediately.

  • Neurological and Mental Health Effects: While uncommon, efavirenz may increase the likelihood of seizures, dizziness, vivid dreams, hallucinations, and sleep disturbances. These symptoms often appear within the initial 1-2 days of treatment and typically subside after 2-4 weeks. Those with a history of seizures, nerve damage, or mental health issues should exercise caution, especially if using other medications that raise seizure risk.

  • Pregnancy Risks: Efavirenz may harm an unborn child, particularly during early pregnancy, by increasing the risk of neural tube defects. It is advisable to avoid pregnancy during treatment and for three months following the last dose.

  • Severe Skin and Allergic Reactions: The medication can cause rashes and severe skin reactions, usually emerging within the first two weeks and resolving in a month. Continue use in case of mild rashes but consult your provider if they worsen. Discontinue use and seek immediate medical help if severe rashes occur alongside fever, discomfort, or swelling.

  • Liver Health: Efavirenz can potentially cause severe liver damage. Regular blood tests will be necessary to monitor liver function. Report symptoms like fatigue, nausea, jaundice, or dark urine to your provider promptly.

  • Cholesterol Levels: This medication may elevate cholesterol and triglycerides, increasing heart attack or stroke risk. Regular monitoring is required, and adjustments to cholesterol-lowering medications may be necessary.

  • Body Fat Changes: Rarely, changes in body fat distribution can occur, affecting areas like the neck, breasts, and abdomen, or causing fat loss from limbs and face. Though the cause is unclear, report any such changes to your provider.

  • Immune System Overactivity: Efavirenz, in combination with other HIV treatments, might lead to immune reconstitution syndrome, where the immune system becomes overly active. This can result in the body attacking its own cells. Report any new symptoms, such as fever or unusual sweating, to your healthcare provider.

  • Drug Interactions: Some medications may affect how efavirenz is processed in your body, impacting its effectiveness and increasing side effects. Inform your provider of all medications you are taking.

Contraindications: Avoid using efavirenz with Zepatier (elbasvir/grazoprevir) as it may cause serious health risks. Always consult your healthcare provider before starting or stopping any medications.

Efavirenz Side Effects

Common side effects:

  • Dizziness
  • Trouble sleeping
  • Drowsiness
  • Unusual dreams
  • Difficulty concentrating
  • Tiredness
  • Nausea
  • Vomiting
  • Diarrhea
  • Headaches
  • Rashes

Serious side effects:

  • Severe allergic reactions (fever, rash, skin blistering)
  • Liver problems (persistent nausea, vomiting, dark urine, yellowing of skin or eyes)
  • Unexplained weight loss
  • Severe tiredness
  • Muscle aches
  • Joint pain
  • Numbness
  • Vision changes
  • Signs of infection (fever, swollen lymph nodes)
  • Mental health changes (depression, anxiety, hallucinations, thoughts of self-harm)

Efavirenz Interactions

Interactions with high risk of serious adverse effects and should be avoided:

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

Efavirenz FAQs
What is the most common side effect of efavirenz?

The most common side effect of efavirenz is central nervous system symptoms, which can include dizziness, insomnia, impaired concentration, and vivid dreams. These symptoms are usually mild to moderate and tend to decrease over time.

Efavirenz is being phased out primarily due to its side effect profile and the availability of newer antiretroviral medications that offer better tolerability and fewer adverse effects. Efavirenz is associated with central nervous system side effects, such as dizziness, insomnia, and vivid dreams, which can impact a patient's quality of life. Additionally, newer medications have improved efficacy and a lower risk of drug interactions, making them more favorable options in the treatment of HIV.

Yes, efavirenz can cause hallucinations as a side effect. It is known to affect the central nervous system, and some patients may experience psychiatric symptoms, including hallucinations, vivid dreams, or other mood changes. If these symptoms occur, it is important to consult a healthcare provider.

Efavirenz should not be taken with certain medications due to potential interactions. These include:- St. John's Wort: It can decrease the effectiveness of efavirenz.- Certain anticonvulsants: Such as carbamazepine, phenobarbital, and phenytoin, which can lower efavirenz levels.- Some antifungal medications: Such as voriconazole, which can have altered levels when taken with efavirenz.- Certain antibiotics: Like rifampin, which can reduce efavirenz levels.- Some benzodiazepines: Such as midazolam and triazolam, which can have increased effects.It is important to consult a healthcare provider for a comprehensive list and guidance on medication interactions with efavirenz.

Efavirenz is classified as a non-nucleoside reverse transcriptase inhibitor (NNRTI). It is used in the treatment of HIV infection.

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