Estradiol

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estradiol

This medication is a hormone (estrogen). It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. This medication may also be used by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure). Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment.
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0.025MG/24HR, Estradiol (1 Patch Weekly)

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CVS

$23.59

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Walgreens

$4.03

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Rite Aid

$15.11

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Walmart

$15.25

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Albertsons

$20.91

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Estradiol savings card

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CVS

$23.59

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Estradiol dosage forms

The average cost for 1 Patch Weekly of Estradiol (estradiol) at 0.025MG/24HR is $4.03 with a free coupon. This is 6.48% off the average retail price of $62.15
DosageQuantityPrice fromPer unit
0.025MG/24HR1 Patch Weekly$4.03$4.03
0.075MG/24HR1 Patch Weekly$4.03$4.03
0.05MG/24HR1 Patch Weekly$4.03$4.03
0.1MG/24HR1 Patch Weekly$4.03$4.03
0.0375MG/24HR1 Patch Weekly$4.03$4.03
0.06MG/24HR1 Patch Weekly$4.03$4.03

Warnings

Estrogens, either used alone or with another hormone (progestin), have rarely caused very serious side effects. Discuss the risks and benefits of hormone treatment with your doctor. Estrogens should not be used to prevent heart disease or dementia. Estrogens can increase the risk of cancer of the uterus (endometrial cancer). Taking a progestin as directed by your doctor can help decrease this risk. Tell your doctor right away if you have any unusual vaginal bleeding. In postmenopausal women, estrogens, taken with or without a progestin, increase the risk of cancer of the breast/ovaries, stroke, dementia, and serious blood clots. When used along with a progestin, estrogens also increase the risk of heart disease (such as heart attacks). The risk for serious side effects may depend on the dose of estrogen and the length of time it is used. This medication should be used at the lowest effective dose and for the shortest amount of time. Discuss the use of this medication with your doctor and check with him/her regularly (for example, every 3 to 6 months) to see if you still need to use this medication. If you will be using this medication long-term, you should have regular complete physical exams (for example, once a year) as directed by your doctor.

Estradiol Side Effects

Skin redness/irritation at the application site, abdominal pain, nausea/vomiting, bloating, breast tenderness, headache, or weight changes may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: nausea/vomiting that doesn't stop, mental/mood changes (such as depression, memory loss), breast lumps, unusual vaginal bleeding (such as spotting, breakthrough bleeding, prolonged/recurrent bleeding), increased or new vaginal irritation/itching/odor/discharge, severe stomach/abdominal pain, yellowing eyes/skin, dark urine, swelling hands/ankles/feet, increased thirst/urination. This medication may rarely cause serious (sometimes fatal) problems from blood clots (such as heart attack, stroke, blood clots in the lungs or legs). Get medical help right away if you have: chest/jaw/left arm pain, unusual sweating, sudden/severe headaches, weakness on one side of the body, confusion, trouble speaking, sudden vision changes, pain/swelling/warmth in the groin/calf, shortness of breath/rapid breathing, sudden dizziness/fainting. A very serious allergic reaction to this product is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Interactions

Some products that may interact with this drug include: aromatase inhibitors (such as anastrozole, exemestane, letrozole), fezolinetant, fulvestrant, ospemifene, raloxifene, tamoxifen, toremifene, tranexamic acid. This medication may interfere with certain lab tests (such as metyrapone test), possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.
Estradiol FAQs
What is Climara used for?

Climara is used for hormone replacement therapy. It is primarily prescribed to treat symptoms associated with menopause, such as hot flashes, vaginal dryness, and prevention of osteoporosis in postmenopausal women.

There is a shortage of estrogen patches due to a combination of factors, including increased demand, manufacturing delays, and supply chain disruptions. These issues can affect the availability of raw materials and the production capacity of pharmaceutical companies, leading to limited supply. Additionally, regulatory challenges and quality control measures can also contribute to the shortage.

Climara, which is a form of hormone replacement therapy, may cause weight gain in some individuals as a side effect. However, weight changes can vary from person to person, and not everyone will experience this effect. It is important for individuals to discuss any concerns about side effects with their healthcare provider.

Estradiol is a form of estrogen, a female hormone involved in various bodily functions. Climara, on the other hand, is a brand name for a transdermal patch that delivers estradiol through the skin. Essentially, Climara is a method of administering estradiol for hormone replacement therapy.

As of the latest available information, Climara has not been officially discontinued. However, availability can vary based on location and supply issues. It is advisable for individuals to check with local pharmacies or healthcare providers for the most current information regarding the availability of Climara.