Propafenone

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This drug is prescribed for managing specific serious irregular heartbeats, such as paroxysmal supraventricular tachycardia and atrial fibrillation, which can be life-threatening. It helps to re-establish a normal heart rhythm and keep a consistent, steady heartbeat. Propafenone is classified as an anti-arrhythmic medication. It operates by inhibiting certain electrical signals in the heart that may lead to an irregular heartbeat. Correcting these irregularities can lower the chance of blood clots, thereby reducing the risk of a heart attack or stroke.
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150MG, Propafenone (30 Tablets)

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CVS

$19.71

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$6.57

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$7.10

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$10.76

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Propafenone savings card

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Propafenone dosage forms

The average cost for 30 Tablets of Propafenone () at 150MG is $6.57 with a free coupon. This is 19.38% off the average retail price of $33.9
DosageQuantityPrice fromPer unit
150MG30 Tablets$6.57$0.22
225MG30 Tablets$8.82$0.29
300MG30 Tablets$10.73$0.36

Warnings

This medication is known to provide significant benefits for individuals with irregular heartbeats. However, in rare instances, it may lead to the development of a new, serious irregular heartbeat. When beginning treatment, your doctor might advise you to remain in a hospital setting to allow for thorough monitoring and immediate medical intervention if necessary. It is important to discuss the potential advantages and risks of this medication with your healthcare provider.

Key safety considerations include:

  • Potential Risks: The possibility of experiencing a new irregular heartbeat, although rare, should be considered.
  • Monitoring: Initial treatment may require hospitalization for close observation and prompt response to any adverse effects.
  • Consultation: Engage in a detailed conversation with your physician regarding how this medication may affect your health.
  • Specific Populations: Inform your doctor if you are pregnant, planning to become pregnant, or have any pre-existing health conditions.
  • Drug Interactions: Be aware of potential interactions with other medications or substances, including alcohol.
  • Overdose Guidance: If an overdose is suspected, seek emergency medical attention immediately.

Always follow your doctor's instructions and report any unusual symptoms or side effects.

Propafenone Side Effects

You may experience some mild side effects while taking this medication, such as dizziness, headache, a metallic or salty taste in the mouth, nausea, vomiting, constipation, anxiety, and tiredness. These effects are usually temporary, but if they persist or worsen, it's important to consult your healthcare provider.

In rare cases, more serious side effects may occur. These include signs of infection like a persistent sore throat, high fever, severe chills, or weakness; signs of liver problems such as continuous nausea, vomiting, stomach pain, yellowing of the eyes or skin, and dark urine; and worsening symptoms of heart failure, like shortness of breath, swelling in the ankles or feet, unusual tiredness, or sudden weight gain. If you experience any of these, seek medical attention promptly.

There are also very serious side effects that require immediate medical help. These include fainting, a faster or more irregular heartbeat, and severe dizziness. Although a severe allergic reaction to this medication is rare, watch for symptoms like a rash, itching or swelling especially on the face, tongue, or throat, severe dizziness, and difficulty breathing. If these occur, get emergency medical assistance.

Remember, this is not an exhaustive list of side effects. If you notice any other unusual symptoms, contact your healthcare provider for advice.

Interactions

Propafenone can interact with several other medications, impacting heart rhythm or the way drugs are processed in the body. Certain drugs like Amiodarone, Dofetilide, Flecainide, Pimozide, procainamide, quinidine, Sotalol, and some antibiotics (macrolides like Clarithromycin, Erythromycin, and quinolones like sparfloxacin) may prolong the QT interval, affecting heart rhythm. Additionally, medications such as asunaprevir, Desipramine, Ketoconazole, Orlistat, Phenobarbital, Phenytoin, Ritonavir, and some HIV protease inhibitors (like tipranavir) can alter how propafenone is eliminated from your body, potentially influencing its effectiveness. Conversely, propafenone may slow down the elimination of drugs such as Digoxin, fezolinetant, imipramine, metoprolol, Propranolol, and Warfarin, possibly affecting their actions.
Propafenone FAQs
What is the black box warning for propafenone?

Propafenone carries a black box warning for its potential to cause new or worsened arrhythmias. It should be used with caution, particularly in patients with structural heart disease, as it can increase the risk of mortality. It is important for healthcare providers to carefully evaluate the risks and benefits before prescribing this medication.

Propafenone is used to treat certain types of serious irregular heartbeats, such as atrial fibrillation and ventricular arrhythmias. It helps to restore normal heart rhythm and maintain a regular, steady heartbeat.

The most common side effects of propafenone include dizziness, fatigue, nausea, vomiting, constipation, and a metallic or unusual taste in the mouth. Some individuals may also experience headache, blurred vision, or difficulty sleeping. It is important for patients to report any persistent or severe side effects to their healthcare provider.

Propafenone can interact with several medications, and it is important to avoid or closely monitor the use of these drugs together. Medications that should not be taken with propafenone or require caution include:1. Beta-blockers: Such as metoprolol or propranolol, as they can increase the risk of side effects.2. Calcium channel blockers: Such as verapamil and diltiazem, which can enhance the effects on heart rate and rhythm.3. Digoxin: Propafenone can increase digoxin levels, leading to toxicity.4. Certain antidepressants: Such as fluoxetine and paroxetine, which can increase propafenone levels.5. CYP2D6 inhibitors: These can increase the concentration of propafenone in the blood.6. Warfarin: Propafenone can increase the effects of warfarin, raising the risk of bleeding.7. Other antiarrhythmics: Such as quinidine or amiodarone, which can increase the risk of arrhythmias.It is essential to consult a healthcare provider before starting or stopping any medications while taking propafenone.

Propafenone is not a beta blocker. It is classified as a Class IC antiarrhythmic medication, which is used to treat certain types of irregular heartbeats. While it does have some beta-blocking properties, its primary action is to slow the conduction of electrical impulses in the heart.