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In some instances, individuals have experienced performing activities such as driving, walking, cooking, eating, making phone calls, or engaging in sexual activities while not fully awake after taking this medication. These episodes, often referred to as "sleep-driving" or sleepwalking, can occur without the person remembering the events. Such behaviors may pose significant risks to both the individual and others, potentially resulting in harm or fatal consequences.

• Contact your healthcare provider immediately if you discover you have engaged in any of these activities after taking the medication.
• Discontinue use of this medication, as well as similar drugs like eszopiclone or zolpidem, if you experience this reaction.

You may experience dizziness, drowsiness, short-term memory loss, or lack of coordination, especially within the first two hours of taking this medication. Taking it just before bedtime can help reduce these effects. If these symptoms persist or worsen, consult your healthcare provider. To minimize dizziness or lightheadedness, rise slowly from sitting or lying down positions.

This medication is intended for your benefit, and many users do not experience serious side effects. However, be alert for severe side effects such as mood changes, confusion, hallucinations, or unusual behavior, and seek medical advice immediately if they occur.

Although rare, a severe allergic reaction may happen. Seek urgent medical attention if you experience symptoms such as rash, itching, swelling of the face, tongue, or throat, severe dizziness, or difficulty breathing. This overview does not include all possible side effects. If you notice any other unusual symptoms, contact your healthcare provider for guidance.

Some substances can interact with this medication, including Melatonin and Sodium Oxybate. Additionally, certain drugs may influence how zaleplon is processed in your body, potentially altering its effectiveness. These include azole antifungals (e.g., Ketoconazole), Cimetidine, rifamycins (e.g., Rifabutin, Rifampin), and seizure medications (e.g., Phenobarbital, Phenytoin), among others.

Combining this medication with other substances that induce drowsiness or affect breathing can heighten the risk of severe side effects, such as slow or shallow breathing and profound drowsiness or dizziness. It is important to inform your doctor or pharmacist if you are using other products that can cause drowsiness, such as opioid pain relievers or cough suppressants (e.g., codeine, hydrocodone), alcohol, marijuana (cannabis), sleep or anxiety medications (e.g., Alprazolam, Lorazepam, Zolpidem), muscle relaxants (e.g., Carisoprodol, Cyclobenzaprine), or antihistamines (e.g., Cetirizine, diphenhydramine).

Always check the labels of all your medications, including those for allergies or cough-and-cold, as they may contain ingredients that cause drowsiness. Consult your pharmacist for advice on using these products safely.