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When using Tenoretic (atenolol / chlorthalidone), it is crucial to be aware of the important safety information and potential risks associated with the medication. Below are key points to consider:

• Do Not Stop Abruptly: Discontinuing Tenoretic suddenly can increase the risk of severe cardiac issues such as chest pain or heart attacks. Consult your doctor before stopping, who may advise a gradual reduction over 1 to 2 weeks. During this period, it is advisable to limit physical activity to reduce cardiac strain. Seek immediate medical attention if you experience symptoms like chest pain, pain spreading to the jaw/neck/arm, excessive sweating, breathing difficulties, or an irregular heartbeat.

• Heart Failure Risk: Tenoretic can potentially exacerbate heart failure because beta blockers can slow heart rate, affecting heart muscle function. If you have existing heart failure, your healthcare professional will carefully weigh the benefits and risks and may monitor your condition more frequently.

• Drug Interactions: Inform your healthcare provider if you are taking calcium channel blockers, such as verapamil or diltiazem, as these can interact with Tenoretic, potentially causing dangerous heart conditions like heart block. Always provide a comprehensive list of your medications to your prescriber.

• Breathing Issues: If you have respiratory problems, such as asthma or chronic obstructive pulmonary disease (COPD), discuss these with your prescriber, as beta blockers may constrict airways, complicating breathing.

• Kidney Function: Since Tenoretic is eliminated via the kidneys, impaired kidney function can lead to drug accumulation and side effects. Alert your healthcare provider if you have kidney issues.

• Fluid and Electrolyte Changes: Tenoretic may cause fluid loss and alter electrolyte balance, especially in those with kidney or liver conditions. This risk is heightened if you are dehydrated or have liver problems.

• Low Blood Sugar Symptoms: Atenolol may obscure symptoms of low blood sugar, making it vital for diabetics to be vigilant. Discuss with your healthcare provider about monitoring blood sugar levels.

• Thyroid Conditions: If you have hyperthyroidism, Tenoretic may mask symptoms such as a rapid heartbeat. Avoid suddenly stopping the medication, as it may worsen your condition or trigger a thyroid storm.

• Gout Risk: Chlorthalidone can increase uric acid, potentially causing gout. If you have a history of gout, inform your healthcare provider to watch for symptoms like painful, swollen joints.

• Pregnancy and Breastfeeding: Tenoretic may harm a developing baby. If pregnant, considering pregnancy, or breastfeeding, discuss potential risks and safer alternatives with your healthcare provider.

Contraindications: Avoid using Tenoretic if you have conditions like a slow heart rate, certain heart blocks, cardiac shock, untreated pheochromocytoma, or if you are unable to urinate. Additionally, do not use if you have a sulfa allergy.

Consult with your healthcare provider to ensure Tenoretic is the right medication for you, and follow their guidance closely to mitigate risks.

Common side effects:

• Dizziness
• Lightheadedness
• Tiredness
• Nausea

• Cold hands and feet

  Less common but important to monitor:

• Dehydration
• Electrolyte imbalance
• Unusually dry mouth
• Excessive thirst
• Muscle cramps or weakness
• Irregular heartbeat
• Confusion
• Very slow heartbeat
• Fainting
• Changes in urination
• Joint pain
• Mood changes
• Blue fingers or toes

• New or worsening symptoms of heart failure

  Serious side effects:

• Decrease in vision
• Eye pain
• Severe allergic reaction

Interactions with high risk of serious adverse effects and should be avoided:

• Dofetilide
• Fingolimod
• Lithium

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Aceclofenac
• Acemetacin
• Acetyldigoxin
• Albuterol
• Amtolmetin Guacil
• Arsenic Trioxide
• Aspirin
• Bepridil
• Bromfenac
• Bufexamac
• Celecoxib
• Ceritinib
• Choline Salicylate
• Clonidine
• Clonixin
• Crizotinib
• Deslanoside
• Desmopressin
• Dexibuprofen
• Dexketoprofen
• Diclofenac
• Diflunisal
• Digitalis
• Digitoxin
• Digoxin
• Diltiazem
• Dipyrone
• Dronedarone
• Droperidol
• Droxicam
• Etodolac
• Etofenamate
• Etoricoxib
• Felbinac
• Fenoldopam
• Fenoprofen
• Fepradinol
• Feprazone
• Floctafenine
• Flufenamic Acid
• Flurbiprofen
• Formoterol
• Ibuprofen
• Indacaterol
• Indomethacin
• Iohexol
• Ketanserin
• Ketoprofen
• Ketorolac
• Lacosamide
• Levalbuterol
• Levomethadyl
• Lornoxicam
• Loxoprofen
• Lumiracoxib
• Meclofenamate
• Mefenamic Acid
• Meloxicam
• Metildigoxin
• Morniflumate
• Nabumetone
• Naproxen
• Nepafenac
• Niflumic Acid
• Nimesulide
• Nimesulide Beta Cyclodextrin
• Olodaterol
• Oxaprozin
• Oxyphenbutazone
• Parecoxib
• Phenylbutazone
• Piketoprofen
• Piroxicam
• Ponesimod
• Proglumetacin
• Propyphenazone
• Proquazone
• Rivastigmine
• Rofecoxib
• Salicylic Acid
• Salmeterol
• Salsalate
• Siponimod
• Sodium Salicylate
• Sotalol
• Sulindac
• Tenoxicam
• Terbutaline
• Tiaprofenic Acid
• Tolfenamic Acid
• Tolmetin
• Valdecoxib
• Verapamil
• Vilanterol