Trudhesa

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Dihydroergotamine is a medication designed to treat migraine and cluster headache attacks, although it is not effective in preventing them. Available as a nasal spray or injection, this drug provides relief from headache pain and symptoms such as sensitivity to light and sound. By working on specific receptors in the brain, including alpha, serotonin, and dopamine receptors, dihydroergotamine helps narrow blood vessels and blocks pain pathways. This action reduces the release of inflammatory chemicals, alleviating headache symptoms and allowing you to resume normal activities sooner. Consult your healthcare provider for personalized medical advice before using dihydroergotamine, as it is crucial to ensure its safety and effectiveness for your condition.
Our Trudhesa coupons are free to use. You can print the coupon, email it to yourself, or receive the Trudhesa coupon via text message. To get your free discount, show the pharmacist your Trudhesa savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Trudhesa prices will update based on your prescription needs. Above our Trudhesa coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Trudhesa savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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1ML of 0.725MG/ACT, Trudhesa (1 Inhaler)

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CVS

$1094.51

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$1080.64

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Walmart

$1116.59

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Walgreens

$1127.58

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Trudhesa savings card

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CVS

$1094.51

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Trudhesa dosage forms

The average cost for 1 Inhaler of Trudhesa at 1ML of 0.725MG/ACT is $1094.51 with a free coupon. This is 27.91% off the average retail price of $3921.15
DosageQuantityPrice fromPer unit
1ML of 0.725MG/ACT1 Inhaler$1094.51$1094.51

Trudhesa Warnings

This medication carries several important safety warnings and precautions that need careful consideration. Patients and healthcare providers should be aware of the following risks and instructions to ensure safe use:

  • Blood Flow Issues: This medication can severely restrict blood flow to the hands, feet, or brain, potentially leading to conditions such as peripheral ischemia or stroke. This risk increases when taken with certain other drugs, including azole antifungals, certain antidepressants, macrolide antibiotics, HIV protease inhibitors, and SSRIs. Inform your healthcare provider about all medications you are taking to avoid dangerous interactions.

  • Heart Health: Dihydroergotamine can constrict blood vessels in the heart, increasing the risk of heart attacks or irregular heartbeats. It is not suitable for individuals with existing heart disease or risk factors like high blood pressure, high cholesterol, obesity, diabetes, or a family history of heart problems. Immediate medical attention is required if chest pain or tightness occurs.

  • Stroke Risk: This medication may increase the risk of stroke or brain damage. It should be used strictly for migraine symptoms, as prescribed. Warning signs such as dizziness, difficulty walking or speaking, confusion, or unilateral weakness should prompt immediate medical consultation.

  • High Blood Pressure: Users without a history of blood pressure issues may experience elevated blood pressure. Those with uncontrolled high blood pressure should avoid this medication.

  • Rebound Headaches: Overuse can lead to medication-overuse headaches. Limit use to less than 10 days per month unless otherwise directed by your healthcare provider.

  • Pregnancy Risks: Dihydroergotamine is not recommended during pregnancy due to potential harm to the mother and unborn child, including the risk of preterm labor and developmental issues in animal studies.

  • Fibrosis: Rare cases of fibrosis in the stomach, lungs, or heart have been reported. Use only as needed and consult your provider if daily use becomes necessary.

  • Nasal Spray Irritation: Users of the nasal spray form may experience nasal irritation, including stuffiness, burning, or bleeding, which typically resolves within four hours. If symptoms persist or are bothersome, contact your healthcare provider.

Contraindications: Do not use this medication if you have any of the following conditions or circumstances:

  • Concurrent use of certain medications like macrolide antibiotics, protease inhibitors, or vasoconstrictive drugs.
  • Recent use of other ergot medications or triptans within 24 hours.
  • Heart conditions or history of heart attack.
  • Uncontrolled high blood pressure.
  • Hemiplegic or basilar migraines.
  • Peripheral arterial disease.
  • Sepsis.
  • Recent vascular surgery.
  • Severe liver or kidney conditions.
  • Pregnancy or breastfeeding.

If you experience an overdose or any severe reactions, seek emergency medical assistance immediately. Always follow your healthcare provider’s guidance and report any unusual symptoms promptly.

Trudhesa Side Effects

Dihydroergotamine can lead to some mild side effects such as a sore or runny nose, throat discomfort, changes in taste, dizziness, or nausea. These effects are generally manageable, but if they persist or worsen, it's important to inform a healthcare professional. Most users of this medication do not experience severe side effects. However, on rare occasions, dihydroergotamine may cause significant blood flow issues. This could manifest as a slow or rapid heartbeat, weakness in the legs, muscle pain in the limbs, tingling or numbness, cold sensations in the hands or feet, or a blue tint on fingers or toes. Severe abdominal pain is also a potential concern.

It is crucial to seek immediate medical attention if you experience severe symptoms such as chest pain, pressure in the jaw or left arm, sudden fatigue, unilateral weakness, difficulty speaking, vision changes, or mental confusion. Though rare, some individuals might experience a severe allergic reaction to dihydroergotamine. Symptoms like a rash, itching, swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing require urgent medical care. Always consult your healthcare provider if you notice any side effects not listed here.

Trudhesa Interactions

Dihydroergotamine may interact with various medications, so it's important to inform your healthcare provider about all medications and supplements you are taking. This includes prescription drugs, over-the-counter medications, vitamins, and herbal supplements.

Certain medications should not be combined with dihydroergotamine due to the risk of serious interactions. These include, but are not limited to, Almotriptan, Amprenavir, Atazanavir, Azithromycin, Boceprevir, Clarithromycin, Cobicistat, Cocaine, Darunavir, Delavirdine, Dirithromycin, Dobutamine, Dopamine, Eletriptan, Ephedrine, Epinephrine, Erythromycin, Fosamprenavir, Frovatriptan, Idelalisib, Indinavir, Itraconazole, Josamycin, Ketoconazole, Letermovir, Lidocaine, Lopinavir, Mepartricin, Midodrine, Mifepristone, Miokamycin, Naratriptan, Nefazodone, Nelfinavir, Norepinephrine, Phenylephrine, Phenylpropanolamine, Posaconazole, Propylhexedrine, Pseudoephedrine, Ritonavir, Rizatriptan, Rokitamycin, Roxithromycin, Saquinavir, Saralasin, Spiramycin, Sumatriptan, Telaprevir, Telithromycin, Tipranavir, Troleandomycin, Vasopressin, Voriconazole, and Zolmitriptan.

Some medications might still be prescribed alongside dihydroergotamine, but only with careful monitoring and possible adjustments to your regimen. These include Abametapir, Alefacept, Berotralstat, Bromocriptine, Ceritinib, Conivaptan, Crizotinib, Dexfenfluramine, Eluxadoline, Enzalutamide, Erdafitinib, Fluconazole, Fluvoxamine, Fosnetupitant, Imatinib, Lanreotide, Lefamulin, Lorlatinib, Lumacaftor, Netupitant, Octreotide, Pazopanib, Propatyl Nitrate, Ranolazine, Ribociclib, Selpercatinib, Sibutramine, Tucatinib, and Voxelotor.

Additionally, using dihydroergotamine with Nitroglycerin or Propranolol may increase the risk of certain side effects. Your doctor will decide the best course of treatment for you, which may involve adjusting the dosage or frequency of use for these medications. Always communicate openly with your healthcare provider to ensure safe and effective use of your medications.

Trudhesa FAQs
What is Trudhesa used for?

Trudhesa is used for the acute treatment of migraine with or without aura in adults.

The cost of Trudhesa can vary depending on factors such as the pharmacy, location, insurance coverage, and any available discounts or patient assistance programs. It is recommended to check with local pharmacies or consult with a healthcare provider or insurance company for the most accurate and up-to-date pricing information.

The new nasal spray for migraines is called Zavzpret (zavegepant). It is a calcitonin gene-related peptide (CGRP) receptor antagonist, designed to provide rapid relief from migraine symptoms.

The cost of Trudhesa without insurance can vary depending on the pharmacy and location. On average, it may range from $500 to $600 for a supply of four nasal spray units. It's advisable to check with local pharmacies for the most accurate pricing. Additionally, patients may explore manufacturer discounts or patient assistance programs to help reduce the cost.

Trudhesa, which contains dihydroergotamine, is not typically known to cause sleepiness as a common side effect. However, individual reactions to medications can vary, and some people might experience drowsiness. If someone experiences unusual side effects, they should consult their healthcare provider.