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Quinine Sulfate

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generic Qualaquin

Quinine, marketed as Qualaquin, is an antimalarial medication used to treat uncomplicated malaria caused by Plasmodium falciparum in individuals aged 16 and older. It is not used for preventing malaria. The drug works by disrupting vital cellular processes in the malaria parasites residing in red blood cells, ultimately killing them. Quinine is usually administered in capsule form every 8 hours. While effective, quinine can cause side effects such as nausea, stomach pain, and vomiting, which may be alleviated by taking the medication with food. It is often not the first choice for treatment due to its numerous side effects, potential drug interactions, and the requirement to be taken alongside other medications like doxycycline or other antimalarials for a complete cure. Additionally, in some cases, another medication such as primaquine may be needed to eliminate parasites in other body tissues and prevent relapse. Before traveling to malaria-prone regions, it's important to consult the latest guidelines and recommendations from health authorities like the United States Centers for Disease Control and discuss them with your healthcare provider. Always seek professional medical advice before starting any new medication.
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324MG, Quinine Sulfate (30 Capsules)

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CVS

$32.58

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$25.17

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$27.10

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$40.04

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$55.14

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Quinine Sulfate savings card

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Quinine Sulfate dosage forms

The average cost for 30 Capsules of Quinine Sulfate (generic Qualaquin) at 324MG is $24.73 with a free coupon. This is 13.69% off the average retail price of $180.6
DosageQuantityPrice fromPer unit
324MG30 Capsules$24.73$0.82

Quinine Sulfate Warnings

Quinine (Qualaquin) is a medication approved by the FDA for the treatment of malaria. However, it is not recommended for managing leg cramps due to its potential to cause serious side effects. Below is a summary of important safety information regarding quinine:

  • Not for Leg Cramps: Quinine should not be used to treat leg cramps. Its effectiveness for this purpose is unproven, and it can cause severe side effects, such as heart and kidney issues, as well as bleeding problems.

  • Low Platelet Counts (Thrombocytopenia): This medication can reduce platelet levels, leading to serious bleeding. Be vigilant for unusual bleeding or bruising and report these to your healthcare provider. Platelet levels typically normalize once treatment is stopped.

  • Hemolytic Anemia: Quinine may lead to hemolytic anemia, causing a reduction in red blood cells. Symptoms to watch for include fatigue, dizziness, and weakness. Regular blood tests are necessary to monitor your blood cell counts.

  • Abnormal Heart Rhythms (QT Prolongation): Quinine can cause QT prolongation, a heart rhythm disorder. The risk is higher if you have heart issues, low electrolyte levels, or take certain other medications. Seek emergency care if you experience chest pain or feel faint.

  • Low Blood Sugar: Quinine can increase insulin levels, potentially causing low blood sugar. It's advisable to have fast-acting sugar sources available while taking this medication. Symptoms of low blood sugar include shakiness and confusion. Consult your provider if these occur.

  • Severe Skin and Allergic Reactions: Serious allergic reactions, including anaphylaxis, and severe skin conditions like Stevens-Johnson syndrome, may occur. If you experience symptoms such as rashes, blisters, or swelling, discontinue use and seek immediate medical attention.

Contraindications: Before using quinine, it's crucial to discuss your medical history with your healthcare provider, especially if you have:

  • A long QT interval
  • Glucose-6-phosphate dehydrogenase (G6PD) deficiency
  • A history of blood problems from quinine
  • Allergies to mefloquine or quinidine
  • Myasthenia gravis
  • Optic neuritis

In case of an overdose, seek emergency medical assistance immediately. Always consult your healthcare provider for personalized advice and to ensure this medication is safe for you.

Quinine Sulfate Side Effects

Common side effects:

  • Headaches
  • Flushing
  • Sweating
  • Nausea
  • Ringing in the ears
  • Temporary hearing loss
  • Dizziness
  • Blurred vision
  • Changes in color vision

Less common but important to monitor:

  • Low blood sugar (hypoglycemia)

Serious side effects:

  • Hemolytic anemia
  • Severe liver problems
  • Kidney issues
  • Serious infections
  • Abnormal heart rhythms
  • Very serious allergic reactions

Quinine Sulfate Interactions

Interactions with high risk of serious adverse effects and should be avoided:

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

Quinine Sulfate FAQs
What is quinine sulfate used for?

Quinine sulfate is used primarily for the treatment of uncomplicated Plasmodium falciparum malaria, a type of malaria caused by a specific parasite. It is often used in combination with other antimalarial medications to enhance effectiveness.

The United States did not ban quinine entirely. However, the FDA has restricted its use due to safety concerns. Quinine was once commonly used to treat leg cramps, but the FDA determined that the risks, including serious side effects like thrombocytopenia and cardiac arrhythmias, outweighed the benefits for this use. Quinine is still approved for the treatment of malaria, but its use is limited to this indication.

Quinidine sulfate is used to treat certain types of irregular heartbeats, such as atrial fibrillation and ventricular arrhythmias. It works by helping to restore a normal heart rhythm and maintain a regular, steady heartbeat.

Yes, quinine sulfate is still available, but its use is limited. It is primarily prescribed for the treatment of uncomplicated malaria caused by Plasmodium falciparum. However, due to potential side effects and the availability of more effective treatments, its use is generally restricted and monitored.

Quinine primarily works by interfering with the growth and reproduction of the malaria parasite in the red blood cells. It is used to treat malaria and can also reduce muscle cramps by affecting the muscle's ability to contract. However, it can cause side effects such as nausea, headache, dizziness, and in some cases, more serious effects like changes in heart rhythm or vision disturbances. It is important to use quinine under medical supervision.