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When using this medication, it is crucial to be aware of the safety information and potential risks involved. Below are key considerations and precautions to keep in mind:

• Do Not Stop Abruptly: Consult your doctor before discontinuing this medication. Stopping suddenly can exacerbate certain conditions, leading to chest pain, heart attack, or irregular heartbeat. Your doctor may advise gradually reducing the dose over 1 to 2 weeks. During this period, limit physical activity to ease heart strain. Seek immediate medical assistance if you experience chest pain, pressure, or pain spreading to the jaw, neck, or arm, alongside symptoms like unusual sweating, breathing difficulties, or a rapid and irregular heartbeat.

• Heart Considerations: Stopping carvedilol (Coreg) suddenly can increase the risk of chest pain and heart attacks. Common symptoms include chest pain, tightness, pain radiating to the arms or neck, shortness of breath, lightheadedness, and fatigue. If discontinuation is necessary, coordinate with your healthcare provider to safely taper the dosage over time.

• Heart Rate and Blood Pressure: Carvedilol (Coreg) may slow your heart rate and lower blood pressure, potentially causing dizziness. Exercise caution when rising from sitting or lying positions to prevent falls. Notify your healthcare provider if your heart rate drops below 55 beats per minute, as this may require a dose adjustment.

• Heart Failure: Those with poorly controlled heart failure should avoid carvedilol (Coreg), as it can worsen their condition. If your symptoms are stable, your provider may consider its use. Report any signs of heart failure, such as fluid retention or difficulty breathing, to your healthcare provider promptly.

• Blood Sugar Levels: Carvedilol (Coreg) can obscure symptoms of low blood sugar, such as a fast heartbeat or tremors, particularly for those taking glucose-lowering medications like glipizide or insulin. Sweating may remain as a warning symptom. Discuss blood sugar monitoring with your healthcare provider.

• Breathing Issues: This medication may constrict lung vessels, making breathing challenging, especially for individuals with asthma or COPD. Inform your doctor about any respiratory conditions before starting carvedilol (Coreg).

• Thyroid Function: Carvedilol (Coreg) can mask symptoms of an overactive thyroid, such as a fast heart rate. Avoid stopping the medication suddenly, as this could worsen thyroid issues.

• Kidney Health: While rare, kidney problems have been observed in some individuals taking carvedilol (Coreg) for heart failure, particularly those with low blood pressure or blood flow issues. Regular lab checks may be necessary to monitor kidney function.

• Allergic Reactions: Beta blockers, including carvedilol (Coreg), can reduce the efficacy of treatments for severe allergic reactions and potentially intensify the reaction. Discuss your allergies and an action plan with your provider.

• Surgical Risks: If you are scheduled for major surgery requiring anesthesia, inform your surgeon about your carvedilol (Coreg) usage. Both beta-blockers and anesthesia can lower heart rate, necessitating close monitoring.

• Eye Surgery: If you are planning cataract surgery, notify your provider about carvedilol (Coreg), as it may cause intraoperative floppy iris syndrome (IFIS). This does not require stopping the medication, but adjustments in surgical technique may be needed.

Contraindications: Avoid using this medication if you have asthma or significant breathing problems, very slow heart rate, certain heart issues (like specific heart block types or cardiac shock without a pacemaker), or severe liver problems. Always consult your healthcare provider if these conditions apply to you.

Common side effects:

• Dizziness
• Lightheadedness
• Drowsiness
• Diarrhea
• Tiredness

• Impotence

  Less common but important to monitor:

• Cold hands and feet

  Serious side effects:

• Very slow heartbeat
• Fainting
• Unusual weakness
• Changes in urine output
• Numbness or tingling in extremities
• Blue fingers or toes
• Easy bruising or bleeding
• Mental changes like confusion or depression
• Worsening heart failure symptoms
• Shortness of breath
• Swelling in the ankles or feet
• Unusual tiredness
• Sudden weight gain
• Severe allergic reactions (skin rash, swelling of face, tongue, or throat, difficulty breathing)
• Bronchospasm (chest tightness and wheezing)

Interactions with high risk of serious adverse effects and should be avoided:

• Colchicine

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Fingolimod
• Afatinib
• Albuterol
• Amiodarone
• Berotralstat
• Betrixaban
• Bupropion
• Ceritinib
• Crizotinib
• DabigatranEtexilate
• Digoxin
• Diltiazem
• Doxorubicin
• DoxorubicinHydrochloride Liposome
• Dronedarone
• Epinephrine
• Fenoldopam
• Fluconazole
• Fluvoxamine
• Formoterol
• Indacaterol
• Iobenguane I 123
• Iobenguane I 131
• Iohexol
• Lacosamide
• Lefamulin
• Levalbuterol
• Miconazole
• Morphine
• MorphineSulfate Liposome
• Nilotinib
• Olodaterol
• Oxymetazoline
• Paroxetine
• Pixantrone
• Ponesimod
• Relugolix
• Rimegepant
• Rivastigmine
• Salmeterol
• Siponimod
• Sulfaphenazole
• Talazoparib
• Terbutaline
• Topotecan
• Ubrogepant
• Valproic Acid
• Venetoclax
• Verapamil
• Vilanterol
• Vincristine
• VincristineSulfate Liposome
• Voriconazole

Interactions with low risk that usually do not require a change in therapy:

• Acarbose
• Aceclofenac
• Acemetacin
• Albiglutide
• Alfuzosin
• Alogliptin
• Amtolmetin Guacil
• Arbutamine
• Aspirin
• Bromfenac
• Bufexamac
• Bunazosin
• Canagliflozin
• Celecoxib
• Chlorpropamide
• Choline Salicylate
• Cimetidine
• Clonixin
• Dapagliflozin
• Dexibuprofen
• Dexketoprofen
• Diclofenac
• Diflunisal
• Dipyrone
• Dobutamine
• Doxazosin
• Droxicam
• Dulaglutide
• Empagliflozin
• Ertugliflozin
• Etodolac
• Etofenamate
• Etoricoxib
• Exenatide
• Felbinac
• Fenoprofen
• Fepradinol
• Feprazone
• Floctafenine
• Flufenamic Acid
• Flurbiprofen
• Glimepiride
• Glipizide
• Glyburide
• Ibuprofen
• Indomethacin
• Insulin Aspart, Recombinant
• Insulin Degludec
• Insulin Detemir
• Insulin Glargine, Recombinant
• Insulin Glulisine
• Insulin Human Inhaled
• Insulin Human Isophane (NPH)
• Insulin Human Regular
• Insulin Lispro, Recombinant
• Ketoprofen
• Ketorolac
• Linagliptin
• Liraglutide
• Lixisenatide
• Lornoxicam
• Loxoprofen
• Lumiracoxib
• Meclofenamate
• Mefenamic Acid
• Meloxicam
• Metformin
• Mibefradil
• Miglitol
• Morniflumate
• Moxisylyte
• Nabumetone
• Naproxen
• Nateglinide
• Nepafenac
• Niflumic Acid
• Nimesulide
• Nimesulide Beta Cyclodextrin
• Oxaprozin
• Oxyphenbutazone
• Parecoxib
• Phenoxybenzamine
• Phentolamine
• Phenylbutazone
• Piketoprofen
• Pioglitazone
• Piroxicam
• Pramlintide
• Pranoprofen
• Prazosin
• Proglumetacin
• Propyphenazone
• Proquazone
• Repaglinide
• Rifampin
• Rifapentine
• Rofecoxib
• Rosiglitazone
• Salicylic Acid
• Salsalate
• Saxagliptin
• Sitagliptin
• Sodium Salicylate
• St John's Wort
• Sulindac
• Tamsulosin
• Tenoxicam
• Terazosin
• Tiaprofenic Acid
• Tolazamide
• Tolbutamide
• Tolfenamic Acid
• Tolmetin
• Trimazosin
• Urapidil
• Valdecoxib
• Vildagliptin