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You might experience mild side effects such as diarrhea, nausea, vomiting, or changes in taste. These are generally not serious, but if they persist or worsen, it is advisable to consult a healthcare professional. Occasionally, you may notice a tablet in your stool, especially if you have certain intestinal conditions.

Be vigilant for more serious side effects, which require immediate medical attention. These include persistent nausea or vomiting, hearing loss, mood changes, muscle weakness, eye issues like drooping eyelids or blurred vision, difficulty speaking, intense stomach pain, dark urine, or yellowing of the skin or eyes.

A rare but severe intestinal condition caused by C. difficile bacteria can occur, either during or after treatment. Symptoms include persistent diarrhea, abdominal pain, or blood/mucus in the stool. If these occur, avoid anti-diarrhea or opioid products, as they can exacerbate symptoms.

Prolonged use of this medication may lead to oral thrush or yeast infections. Look out for symptoms such as white patches in the mouth or changes in vaginal discharge.

Seek emergency medical help if you experience severe dizziness, fainting, or an irregular heartbeat. Although rare, serious allergic reactions can occur. Watch for symptoms like persistent fever, swollen lymph nodes, rash, itching or swelling of the face, tongue, or throat, severe dizziness, or trouble breathing.

This summary does not cover all possible side effects. If you notice other unusual symptoms, contact a healthcare provider.

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Clarithromycin may interact with several medications, potentially affecting heart rhythm (QT prolongation). This includes drugs like amiodarone, disopyramide, dofetilide, pacritinib, pimozide, procainamide, quinidine, and sotalol. Additionally, some medications can change how clarithromycin is removed from the body, influencing its effectiveness. Examples include efavirenz, nevirapine, posaconazole, and rifamycins like rifabutin. Clarithromycin can also slow down the elimination of other drugs, impacting their function. Affected drugs include colchicine, digoxin, certain medications for erectile dysfunction or pulmonary hypertension (such as sildenafil and tadalafil), ergot alkaloids (like ergotamine and dihydroergotamine), flibanserin, some statins (including lovastatin and simvastatin), tamsulosin, tolvaptan, and ticagrelor.